Pro-arrhythmic effects of elevated branched chain amino acid levels.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular research"
DOI: 10.1093/cvr/cvab207
Abstract: AIM Cardiac arrhythmias comprise a major health and economic burden and are associated with significant morbidity and mortality, including cardiac failure, stroke and sudden cardiac death (SCD). Development of efficient preventive and therapeutic strategies is… read more here.
Keywords: branched chain; pro arrhythmic; amino acid; chain amino ... See more keywords
Cardiac resynchronization is pro-arrhythmic in the absence of reverse ventricular remodelling: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Research"
DOI: 10.1093/cvr/cvy182
Abstract: Aims Cardiac resynchronization therapy (CRT) has been shown to reduce mortality and heart failure (HF) hospitalization but its effects on the rate of ventricular arrhythmias (VAs) appears to be neutral. We hypothesize that CRT with… read more here.
Keywords: pro arrhythmic; analysis; absence reverse; cardiac resynchronization ... See more keywords
Chronically altered ventricular activation causes pro-arrhythmic cardiac electrical remodelling in the chronic AV block dog model
Sign Up to like & getrecommendations! Published in 2022 at "Europace"
DOI: 10.1093/europace/euac164
Abstract: Abstract Aims Altered ventricular activation (AVA) causes intraventricular mechanical dyssynchrony (MD) and impedes contraction, promoting pro-arrhythmic electrical remodelling in the chronic atrioventricular block (CAVB) dog. We aimed to study arrhythmogenic and electromechanical outcomes of different… read more here.
Keywords: crt; electrical remodelling; block; dog ... See more keywords
β-Adrenergic stimulation induces pro-arrhythmic activity in the caval vein myocardial tissue
Sign Up to like & getrecommendations! Published in 2017 at "Doklady Biological Sciences"
DOI: 10.1134/s0012496617050027
Abstract: Electrical activity of the right superior vena cava (SVC) is considered as a source of the atrial fibrillation. We have shown that bioelectrical properties of the SVC myocardium differ from those of the working atrial… read more here.
Keywords: pro arrhythmic; adrenergic stimulation; stimulation induces; induces pro ... See more keywords
Human Cardiomyocyte Progenitor Cells in Co-culture with Rat Cardiomyocytes Form a Pro-arrhythmic Substrate: Evidence for Two Different Arrhythmogenic Mechanisms
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2017.00797
Abstract: Background: Cardiomyocyte progenitor cells (CMPCs) are a promising cell source for regenerative cell therapy to improve cardiac function after myocardial infarction. However, it is unknown whether undifferentiated CMPCs have arrhythmogenic risks. We investigate whether undifferentiated,… read more here.
Keywords: cardiomyocyte progenitor; pro arrhythmic; cmpcs; form pro ... See more keywords
Action Potential Recording and Pro-arrhythmia Risk Analysis in Human Ventricular Trabeculae
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2017.01109
Abstract: To assess drug-induced pro-arrhythmic risk, especially Torsades de Pointe (TdP), new models have been proposed, such as in-silico modeling of ventricular action potential (AP) and stem cell-derived cardiomyocytes (SC-CMs). Previously we evaluated the electrophysiological profile… read more here.
Keywords: pro arrhythmic; risk; drug; ventricular trabeculae ... See more keywords