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Published in 2022 at "Atherosclerosis"
DOI: 10.1016/j.atherosclerosis.2022.01.015
Abstract: BACKGROUND AND AIMS A complex interplay among chronic kidney disease (CKD), lipid metabolism and aortic calcification has been recognized. Here we investigated the influence of kidney function on PCSK9 levels and its potential direct action…
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Keywords:
pcsk9;
promotes arterial;
calcification;
pro calcific ... See more keywords
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Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12081157
Abstract: Medial vascular calcification is common in chronic kidney disease (CKD) and is closely linked to hyperphosphatemia. Vascular smooth muscle cells (VSMCs) can take up pro-calcific properties and actively augment vascular calcification. Various pro-inflammatory mediators are…
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Keywords:
periostin;
pro calcific;
calcification;
vascular smooth ... See more keywords
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Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032667
Abstract: Calcification starts with hydroxyapatite (HA) crystallization on cell membranous components, as with aortic valve interstitial cells (AVICs), wherein a cell-membrane-derived substance containing acidic phospholipids (PPM/PPLs) acts as major crystal nucleator. Since nucleic acid removal is…
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Keywords:
rrna nuclear;
aortic valve;
calcification;
pro calcific ... See more keywords