A Unified View of Assessing the Pro‐oxidant versus Antioxidant Nature of Amyloid Beta Conformers
Sign Up to like & getrecommendations! Published in 2018 at "ChemBioChem"
DOI: 10.1002/cbic.201800446
Abstract: Transition‐metal‐catalyzed oxidative stress is a widespread concern in the pathogenesis of Alzheimer's disease. However, the exact role of amyloid beta oligomers towards oxidative stress is widely debated. Assessing the oxidative nature of the oligomers in… read more here.
Keywords: amyloid beta; pro oxidant; unified view; nature ... See more keywords
Glucose Promotes a Pro‐Oxidant and Pro‐Inflammatory Stromal Microenvironment Which Favors Motile Properties in Breast Tumor Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25650
Abstract: Chronic inflammation and metabolic reprogramming have been proposed as hallmarks of cancer development. Currently, many of the functional clues between these two phenomena are studied under the integrative view of functional stroma–epithelia interaction. It has… read more here.
Keywords: pro oxidant; glucose promotes; motile properties; pro inflammatory ... See more keywords
Biodegradation kinetic modeling of pro-oxidant filled polypropylene composites under thermophilic composting conditions after abiotic treatment
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-11766-0
Abstract: This work aims at modeling and characterizing the kinetics of biodegradation of polypropylene loaded with cobalt stearate as pro-oxidant after abiotic treatment. Eight films of these composites were prepared using different pro-oxidant loadings. These films… read more here.
Keywords: pro oxidant; abiotic treatment; carbon; hydrolyzable carbon ... See more keywords
Iron, Dopamine, and α-Synuclein Interactions in at-Risk Dopaminergic Neurons in Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Bulletin"
DOI: 10.1007/s12264-018-0209-7
Abstract: Parkinson’s disease (PD) is recognized as the second most common neurodegenerative disorder after Alzheimer disease. Although a fascinating 200-year journey of research has revealed the multifaceted nature of PD [1, 2], its fundamental features are… read more here.
Keywords: pro oxidant; dopamine; parkinson disease; dopaminergic neurons ... See more keywords
Iron ions chelation-based antioxidant potential vs. pro-oxidant risk of ferulic acid: A DFT study in aqueous phase
Sign Up to like & getrecommendations! Published in 2020 at "Computational and Theoretical Chemistry"
DOI: 10.1016/j.comptc.2020.112905
Abstract: Abstract Antioxidant activities based on iron ions chelation of ferulic acid (FA) in competition with its pro-oxidant risk have been investigated. Reaction enthalpies (ΔrH0) and Gibbs free energies (ΔrG0) of chelation reaction between the neutral… read more here.
Keywords: pro oxidant; iron ions; oxidant risk;
Nutritional, chemical and antioxidant/pro-oxidant profiles of silverskin, a coffee roasting by-product.
Sign Up to like & getrecommendations! Published in 2018 at "Food chemistry"
DOI: 10.1016/j.foodchem.2017.03.106
Abstract: Coffee silverskin (a coffee roasting by-product) contains high amounts of dietary fibre (49% insoluble and 7% soluble) and protein (19%). Potassium (∼5g/100g), magnesium (2g/100g) and calcium (0.6g/100g) are the major macrominerals. The vitamin E profile… read more here.
Keywords: pro oxidant; silverskin coffee; coffee roasting; roasting product ... See more keywords
Assessment of pro-oxidant activity of natural phenolic compounds in bio-polyesters
Sign Up to like & getrecommendations! Published in 2018 at "Polymer Degradation and Stability"
DOI: 10.1016/j.polymdegradstab.2018.05.003
Abstract: Abstract In this work, natural phenolic compounds, such as Vanillic Acid (VA), Ferulic Acid (FA) and Thymol (Th), at very high concentrations, have been considered as pro-oxidant agents for Polylactic acid (PLA). Specifically, thin films… read more here.
Keywords: degradation; pro oxidant; natural phenolic; oxidant activity ... See more keywords
Vitamin E d-α-Tocopheryl Polyethylene Glycol Succinate (TPGS) Provokes Cell Death in Human Neuroblastoma SK-N-SH Cells via a Pro-Oxidant Signaling Mechanism.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.8b00138
Abstract: Neuroblastoma (NB) is the most common neoplasm during infancy. Unfortunately, NB is still a lethal cancer. Therefore, innovative curative therapies are immediately required. In this study, we showed the prodeath activity of TPGS in human… read more here.
Keywords: pro oxidant; via pro; cell death; cells via ... See more keywords
Chlorine-Doped Graphene Quantum Dots with Enhanced Anti- and Pro-Oxidant Properties.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b03194
Abstract: Production or elimination of highly reactive oxygen species is critical in antioxidant, photodynamic, therapeutic, and antibacterial applications. Recent studies have demonstrated that graphene quantum dots (GQDs) possess anti- and pro-oxidant properties simultaneously. However, their efficiency… read more here.
Keywords: pro oxidant; graphene quantum; oxidant properties; quantum dots ... See more keywords
Glutathione-Depleting Pro-Oxidant as a Selective Anticancer Therapeutic Agent
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.9b00140
Abstract: A main challenge in the development of anticancer drugs that eradicate cancer cells specifically with minimal toxicity to normal cells is to identify the cancer-specific properties. Cancer cells sustain a higher level of reactive oxygen… read more here.
Keywords: pro oxidant; b2c; cancer cells; cancer ... See more keywords
New insights into the competition between antioxidant activities and pro-oxidant risks of rosmarinic acid
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d1ra07599c
Abstract: Direct and indirect antioxidant activities of rosmarinic acid (RA) based on HOO˙/CH3OO˙ radical scavenging and Fe(iii)/Fe(ii) ion chelation were theoretically studied using density functional theory at the M05-2X/6-311++G(2df,2p) level of theory. First, four antioxidant mechanisms… read more here.
Keywords: rosmarinic acid; oxidant risks; insights competition; pro oxidant ... See more keywords