PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Oncogene"
DOI: 10.1038/s41388-017-0040-z
Abstract: High grade serous carcinoma (HGSC) is the most common subtype of ovarian cancer and it is now widely accepted that this disease often originates from the fallopian tube epithelium. PAX8 is a fallopian tube lineage… read more here.
Keywords: pax8; grade serous; fallopian tube; high grade ... See more keywords
Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells
Sign Up to like & getrecommendations! Published in 2020 at "Oncotarget"
DOI: 10.18632/oncotarget.27545
Abstract: SYK has been reported to possess both tumour promotor and repressor activities and deletion has been linked to a pro-proliferative / pro-invasive phenotype in breast tumours. It is unclear whether this is a consequence of… read more here.
Keywords: phenotype; breast; kinase; pro proliferative ... See more keywords