Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01845d
Abstract: Vascularized composite allotransplantation (VCA) is a restorative option for patients suffering from severe tissue defects not amenable to conventional reconstruction. However, the toxicities associated with life-long multidrug immunosuppression to enable allograft survival and induce immune… read more here.
Keywords: vascularized composite; survival; pro regenerative; allograft survival ... See more keywords
ADM Scaffolds Generate a Pro-regenerative Microenvironment During Full-Thickness Cutaneous Wound Healing Through M2 Macrophage Polarization via Lamtor1
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.00657
Abstract: Adult mammalian skin has a defective regenerative capacity following full-thickness cutaneous injury; this defect overshadows the complete physiological functions of the skin. Immune-mediated skin reconstruction driven by biological scaffolds is a recently developed innovative repair… read more here.
Keywords: wound healing; full thickness; adm scaffolds; pro regenerative ... See more keywords
Renal Regenerative Potential of Extracellular Vesicles Derived from miRNA-Engineered Mesenchymal Stromal Cells
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20102381
Abstract: Extracellular vesicles (EVs) derived from mesenchymal stromal cells (MSCs) possess pro-regenerative potential in different animal models with renal injury. EVs contain different molecules, including proteins, lipids and nucleic acids. Among the shuttled molecules, miRNAs have… read more here.
Keywords: extracellular vesicles; mesenchymal stromal; stromal cells; pro regenerative ... See more keywords
Anti-Inflammatory and Pro-Regenerative Effects of Hyaluronan-Chitlac Mixture in Human Dermal Fibroblasts: A Skin Ageing Perspective
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14091817
Abstract: Inflammation and the accumulation of reactive oxygen species (ROS) play an important role in the structural and functional modifications leading to skin ageing. The reduction of inflammation, cellular oxidation and dermal extracellular matrix (ECM) alterations… read more here.
Keywords: dermal fibroblasts; inflammation; skin ageing; ecm molecules ... See more keywords