Upregulation of Pro-Tumor Nitric Oxide by Anti-Tumor Photodynamic Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2019.113750
Abstract: Many malignant tumors use endogenous nitric oxide (NO) to promote survival, growth, and metastatic migration. This NO, which is typically generated by inducible nitric oxide synthase (iNOS), can also antagonize various anti-cancer therapies and its… read more here.
Keywords: upregulation pro; photodynamic therapy; pro tumor; nitric oxide ... See more keywords
Dysregulated metabolism: A friend-to-foe skewer of macrophages
Sign Up to like & getrecommendations! Published in 2022 at "International Reviews of Immunology"
DOI: 10.1080/08830185.2022.2095374
Abstract: Abstract Metabolic reprogramming is a hallmark of solid cancers. Macrophages as major constituents of immune system take important roles in regulation of tumorigenesis. Pro-tumor M2 macrophages preferentially use oxidative phosphorylation (OXPHOS) to meet their metabolic… read more here.
Keywords: metabolism; phenotype; pro tumor; glycolysis ... See more keywords
Structural characterization and in vivo pro-tumor properties of a highly conserved matrikine
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24894
Abstract: Elastin-derived peptides (EDPs) exert protumor activities by increasing tumor growth, migration and invasion. A number of studies have highlighted the potential of VGVAPG consensus sequence-derived elastin-like polypeptides whose physicochemical properties and biocompatibility are particularly suitable… read more here.
Keywords: tumor properties; vivo pro; characterization vivo; pro tumor ... See more keywords
MicroRNA-383: A tumor suppressor miRNA in human cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.955486
Abstract: Downregulated expression of anti-tumor miR-383 has been found in many kinds of cancer. MiR-383 family members can directly target the 3′-untranslated region (3′-UTR) of the mRNA of some pro-tumor genes to attenuate several cancer-related processes,… read more here.
Keywords: anti tumor; tumor effects; pro tumor; mir 383 ... See more keywords
Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.01878
Abstract: Plasmacytoid dendritic cells are the most efficient producers of type I interferons, viz. IFNα, in the body and thus have the ability to influence anti-tumor immune responses. But repression of effective intra-tumoral pDC activation is… read more here.
Keywords: pro tumor; dendritic cells; plasmacytoid dendritic; intra tumoral ... See more keywords
Pro-tumor γδ T Cells in Human Cancer: Polarization, Mechanisms of Action, and Implications for Therapy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.02186
Abstract: The tumor immune microenvironment contributes to tumor initiation, progression and response to therapy. Among the immune cell subsets that play a role in the tumor microenvironment, innate-like T cells that express T cell receptors composed… read more here.
Keywords: human cancer; tumor cells; polarization; pro tumor ... See more keywords
Evidence that oral immunoglobulins (KMP01) suppress pro-tumor inflammation in rectal carcinoma: Case report and treatment concept.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of clinical pharmacology and therapeutics"
DOI: 10.5414/cp204326
Abstract: BACKGROUND A female patient aged 49 years with a rectal adenocarcinoma underwent tumor resection and multiple follow-up surgical operations whilst receiving compassionate therapy with polyvalent immunoglobulins derived from bovine colostrum (KMP01), a potential modulator of… read more here.
Keywords: tumor inflammatory; inflammatory response; pro tumor; treatment ... See more keywords
The pro-tumor effect and the anti-tumor effect of neutrophils extracellular traps.
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience trends"
DOI: 10.5582/bst.2019.01326
Abstract: Significant advances in our understanding of neutrophil biology were made in the past several years. A newly discovered mechanism was discovered, the formation of neutrophils extracellular traps (NETs). The structure of NETs is composed of… read more here.
Keywords: tumor; effect; anti tumor; pro tumor ... See more keywords