SFTS bunyavirus NSs protein sequestrates mTOR into inclusion bodies and deregulates mTOR‐ULK1 signaling, provoking pro‐viral autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28371
Abstract: Autophagy is emerging as a critical player in host defense against diverse infections, in addition to its conserved function to maintain cellular homeostasis. Strikingly, some pathogens have evolved strategies to evade, subvert or exploit different… read more here.
Keywords: mtor ulk1; viral autophagy; pro viral; inclusion bodies ... See more keywords
HIV serology false positivity among expatriates from Africa: a screening dilemma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Microbiology"
DOI: 10.1099/jmm.0.001186
Abstract: HIV prevalence in Oman is low (5 %). HIV screening is performed at regional public health laboratories as part of a medical fitness programme for residency applicants. We conducted a retrospective evaluation of indeterminate serology results… read more here.
Keywords: hiv serology; hiv; serology; prevalence ... See more keywords
Murine coronavirus infection activates AhR in an IDO1-independent manner contributing to cytokine modulation and pro-viral TiPARP expression.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of virology"
DOI: 10.1128/jvi.01743-19
Abstract: The aryl hydrocarbon receptor (AhR) is a cytoplasmic receptor/transcription factor that modulates several cellular and immunological processes following activation by pathogen-associated stimuli, though its role during virus infection is largely unknown. Here, we show that… read more here.
Keywords: expression; activation; role; pro viral ... See more keywords
Pro-Viral and Anti-Viral Roles of the RNA-Binding Protein G3BP1
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DOI: 10.3390/v15020449
Abstract: Viruses depend on host cellular resources to replicate. Interaction between viral and host proteins is essential for the pathogens to ward off immune responses as well as for virus propagation within the infected cells. While… read more here.
Keywords: binding protein; rna binding; protein g3bp1; pro viral ... See more keywords