Articles with "proadm" as a keyword



Clinical utility of biomarkers in heart failure

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Published in 2017 at "European Journal of Heart Failure"

DOI: 10.1002/ejhf.893

Abstract: The study on the prognostic utility of midregional pro-adrenomedullin (MR-proADM) following decompensation for systolic heart failure from the Interdisciplinary Network Heart Failure programme extends and corroborates insights gained from several previous studies on this emerging… read more here.

Keywords: clinical utility; proadm; heart; heart failure ... See more keywords

Prognostic value of plasma MR-proADM vs NT-proBNP for heart failure in people with type 2 diabetes: the SURDIAGENE prospective study

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Published in 2018 at "Diabetologia"

DOI: 10.1007/s00125-018-4727-7

Abstract: Aims/hypothesisN-terminal pro-B-type natriuretic peptide (NT-proBNP) is the gold standard prognostic biomarker for diagnosis and occurrence of heart failure. Here, we compared its prognostic value for the occurrence of congestive heart failure with that of plasma… read more here.

Keywords: heart; people type; heart failure; type diabetes ... See more keywords

Elevated levels of adrenomedullin in eutopic endometrium and plasma from women with endometriosis.

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Published in 2018 at "Fertility and sterility"

DOI: 10.1016/j.fertnstert.2018.02.004

Abstract: OBJECTIVE To test adrenomedullin (Adm, ADM) as a downstream target of signal transducer and activator of transcription 3 (STAT3) in endometrial cells and to test midregional proadrenomedullin (MR-proADM) as a biomarker of endometriosis. DESIGN Cross-sectional… read more here.

Keywords: eutopic endometrium; plasma women; women endometriosis; proadm ... See more keywords

Ultra-sensitive Quantification of Mid-regional Proadrenomedullin in Human Plasma Using Micro-liquid Chromatography Coupled to Quadrupole Time-of-Flight Mass Spectrometry

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Published in 2025 at "ACS Omega"

DOI: 10.1021/acsomega.4c11248

Abstract: Mid-regional proadrenomedullin (MR-proADM) has been suggested to be a powerful biomarker for the onset, progression, and mortality of various diseases. To achieve sensitive quantification of MR-proADM without cross-reactivity, we established micro-liquid chromatography coupled to the… read more here.

Keywords: regional proadrenomedullin; method; quantification; mid regional ... See more keywords

Association of mid-regional pro-adrenomedullin with office and 24-h ambulatory blood pressure in a Swiss general population sample

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Published in 2024 at "Journal of Hypertension"

DOI: 10.1097/hjh.0000000000003866

Abstract: Objective: Adrenomedullin (ADM) is a potent vasodilator. The association between plasma ADM levels and blood pressure (BP) remains unclear. We assessed the association between mid-regional-pro-ADM (MR-proADM) and BP in a multicenter population- and family-based cohort.… read more here.

Keywords: baseline; office; proadm; association ... See more keywords

Plasma mid‐regional pro‐adrenomedullin: A biomarker of the ischemic penumbra in hyperacute stroke

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Published in 2022 at "Brain Pathology"

DOI: 10.1111/bpa.13110

Abstract: Reperfusion therapy has improved the outcomes of ischemic stroke but also emphasized the importance of ischemic penumbra. However, blood biomarkers are currently unavailable for this region. Adrenomedullin (ADM) is a neuroprotective peptide, secreted in a… read more here.

Keywords: biomarker; proadm; ischemic penumbra; mid regional ... See more keywords
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MR‐proADM as marker of endotheliitis predicts COVID‐19 severity

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Published in 2021 at "European Journal of Clinical Investigation"

DOI: 10.1111/eci.13511

Abstract: Early identification of patients at high risk of progression to severe COVID‐19 constituted an unsolved challenge. Although growing evidence demonstrates a direct association between endotheliitis and severe COVID‐19, the role of endothelial damage biomarkers has… read more here.

Keywords: proadm marker; endotheliitis predicts; proadm; endotheliitis ... See more keywords

Association of circulating MR-proADM with all-cause and cardiovascular mortality in the general population: Results from the KORA F4 cohort study

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0262330

Abstract: Background and aim Despite its vasodilatory effect, adrenomedullin and its surrogate mid-regional pro-adrenomedullin (MR-proADM) have been found to be positively associated with all-cause and cardiovascular mortality. However, the underlying mechanisms thereof remain unclear and the… read more here.

Keywords: proadm; mortality; cause cardiovascular; association ... See more keywords

The kinetic profiles of copeptin and mid regional proadrenomedullin (MR-proADM) in pediatric lower respiratory tract infections

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0264305

Abstract: Background Kinetics of copeptin and mid regional proadrenomedullin (MR-proADM) during febrile pediatric lower respiratory tract infections (LRTI) are unknown. We aimed to analyze kinetic profiles of copeptin and MR-proADM and the impact of clinical and… read more here.

Keywords: day; proadm; regional proadrenomedullin; proadrenomedullin proadm ... See more keywords

Biomarker response and therapy prediction in renal denervation therapy – the role of MR-proadrenomedullin in a multicenter approach

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Published in 2017 at "Biomarkers"

DOI: 10.3109/1354750x.2016.1172112

Abstract: Abstract Background: Renal denervation has been proposed as a therapeutic option in patients with resistant hypertension. Circulating blood borne biomarkers might be helpful to identify individuals responding to RDN therapy. MR-proADM is a strong prognostic… read more here.

Keywords: therapy; proadm; renal denervation; multicenter approach ... See more keywords

Synergistic effect of myocardial injury and mid-regional proAdrenomedullin elevation in determining clinical outcomes of SARS-CoV-2 patients

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Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.929408

Abstract: Objective Coronavirus disease 2019 (COVID-19) is a systemic disease induced by SARS-CoV-2 causing myocardial injury. To date, there are few data on the correlation between mid-regional proAdrenomedullin (MR-proADM) and myocardial injury. The aim of this… read more here.

Keywords: myocardial injury; proadm; mid regional; mortality ... See more keywords