Roxadustat attenuates hyperoxia-induced lung injury by upregulating proangiogenic factors in newborn mice.
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DOI: 10.1016/j.pedneo.2021.03.012
Abstract: BACKGROUND Premature infants who require oxygen therapy for respiratory distress syndrome often develop bronchopulmonary dysplasia, a chronic lung disease characterized by interrupted alveologenesis. Disrupted angiogenesis inhibits alveologenesis; however, the mechanisms through which disrupted angiogenesis affects… read more here.
Keywords: hyperoxia induced; angiogenesis; induced lung; lung injury ... See more keywords