Sustained MK-801 induced deficit in a novel probabilistic reversal learning task
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DOI: 10.3389/fphar.2022.898548
Abstract: Cognitive flexibility, the ability to adapt to unexpected changes, is critical for healthy environmental and social interactions, and thus to everyday functioning. In neuropsychiatric diseases, cognitive flexibility is often impaired and treatment options are lacking.… read more here.
Keywords: time; reversal learning; based prl; probabilistic reversal ... See more keywords
Computational analysis of probabilistic reversal learning deficits in male subjects with alcohol use disorder
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Psychiatry"
DOI: 10.3389/fpsyt.2022.960238
Abstract: Background Alcohol use disorder is characterized by perseverative alcohol use despite negative consequences. This hallmark feature of addiction potentially relates to impairments in behavioral flexibility, which can be measured by probabilistic reversal learning (PRL) paradigms.… read more here.
Keywords: use disorder; reversal learning; probabilistic reversal; alcohol use ... See more keywords