Articles with "probe drug" as a keyword



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Characterization of the in vitro CYP450 mediated metabolism of the polymorphic CYP2D6 probe drug codeine in horses.

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Published in 2019 at "Biochemical pharmacology"

DOI: 10.1016/j.bcp.2019.07.005

Abstract: Despite their widespread popularity as sport and companion animals and published and anecdotal reports of vast difference in drug disposition and pharmacokinetics between individuals, studies describing equine drug metabolism are limited. It has been theorized… read more here.

Keywords: codeine; polymorphic cyp2d6; drug; mediated metabolism ... See more keywords