Synthesis of a fluorescent photoaffinity probe of OSW-1 by site-selective acylation of an inactive congener and biological evaluation.
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DOI: 10.1039/c6cc08955k
Abstract: A novel fluorescent photoaffinity probe of OSW-1 was prepared in two steps from a naturally occurring inactive congener by a sequential site-selective acylation strategy using Me2SnCl2. It displayed highly potent anticancer activity and a similar… read more here.
Keywords: photoaffinity probe; site selective; selective acylation; probe osw ... See more keywords