A bioorthogonal 'turn-on' fluorescent probe for tracking mitochondrial nitroxyl formation.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c6cc09082f
Abstract: A bioreductant-resistant 'turn-on' chemodosimetric fluorescent probe Mito-1 has been developed for the detection of mitochondrial HNO in live cells. Mito-1 enables the detection of HNO as low as ∼18 nM. It has the capability to… read more here.
Keywords: turn fluorescent; fluorescent probe; mitochondrial nitroxyl; bioorthogonal turn ... See more keywords
A fluorogenic probe for tracking GSH flux in developing neurons.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc07753g
Abstract: Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a… read more here.
Keywords: flux developing; gsh flux; probe; developing neurons ... See more keywords