Photo‐affinity and Metabolic Labeling Probes Based on the Opioid Alkaloids
Sign Up to like & getrecommendations! Published in 2024 at "ChemBioChem"
DOI: 10.1002/cbic.202300841
Abstract: The opioids are powerful analgesics yet possess contingencies that can lead to opioid‐use disorder. Chemical probes derived from the opioid alkaloids can provide deeper insight into the molecular interactions in a cellular context. Here, we… read more here.
Keywords: photo; photo affinity; affinity metabolic; probes based ... See more keywords
Fluorescent hydrogen sulfide probes based on azonia-cyanine dyes and their imaging applications in organelles.
Sign Up to like & getrecommendations! Published in 2019 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2019.03.057
Abstract: Three hydrogen sulfide (H2S) probes based on an azonia-cyanine skeleton were successfully designed and prepared. Probe 1a, containing 4-chloro-7-nitro-1,2,3-benzoxadiazole connected to the cyanine dye, had an emission at 660 nm that was enhanced 4.5-fold by the… read more here.
Keywords: based azonia; hydrogen; probes based; hydrogen sulfide ... See more keywords
Development of Photocrosslinking Probes Based on Huwentoxin-IV to Map the Site of Interaction on Nav1.7
Sign Up to like & getrecommendations! Published in 2019 at "Cell Chemical Biology"
DOI: 10.1016/j.chembiol.2019.10.011
Abstract: Summary Voltage-gated sodium (Nav) channels respond to changes in the membrane potential of excitable cells through the concerted action of four voltage-sensor domains (VSDs). Subtype Nav1.7 plays an important role in the propagation of signals… read more here.
Keywords: based huwentoxin; development photocrosslinking; probes based; photocrosslinking probes ... See more keywords
The near-infrared fluorescent probes based on phenoxazine for the rapid detection of hypochlorous acid
Sign Up to like & getrecommendations! Published in 2020 at "Dyes and Pigments"
DOI: 10.1016/j.dyepig.2020.108404
Abstract: Abstract Hypochlorous acid (HOCl) is tightly related with a series of diseases, and plays an important part in biological processes. Herein, we designed and synthesized two “turn-on” near-infrared (NIR) probes (BC-2 and BC-3) based on… read more here.
Keywords: based phenoxazine; probes based; infrared fluorescent; near infrared ... See more keywords
Shortwave-Infrared Fluorescent Molecular Imaging Probes Based on π-Conjugation Extended Indocyanine Green.
Sign Up to like & getrecommendations! Published in 2021 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.1c00253
Abstract: Recently, shortwave-infrared (SWIR) fluorescence imaging for the optical diagnostics of diseases has attracted much attention as a new noninvasive imaging modality. For this application, the development of SWIR molecular imaging probes with high biocompatibility is… read more here.
Keywords: probes based; imaging probes; shortwave infrared; conjugation extended ... See more keywords
Discovery of GPR84 Fluorogenic Probes Based on a Novel Antagonist for GPR84 Bioimaging.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c00359
Abstract: GPR84 is a promising therapeutic target and biomarker for a range of diseases. In this study, we reported the discovery of BINOL phosphate (BINOP) derivatives as GPR84 antagonists. By investigating the structure-activity relationship, we identified… read more here.
Keywords: fluorogenic probes; gpr84; discovery gpr84; gpr84 fluorogenic ... See more keywords
Fluorogenic NIR-probes based on 1,2,4,5-tetrazine substituted BF2-azadipyrromethenes.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc06545k
Abstract: A series of 1,2,4,5-tetrazine integrated near infrared (NIR) fluorophores based on the BF2 azadipyrromethene (NIR-AZA) class has been synthesised and their ability to modulate emission from low to high in response to Diels-Alder cycloaditions has… read more here.
Keywords: fluorogenic nir; probes based; based tetrazine; nir ... See more keywords
Customized MFM probes based on magnetic nanorods.
Sign Up to like & getrecommendations! Published in 2020 at "Nanoscale"
DOI: 10.1039/d0nr00322k
Abstract: Focused Electron Beam Induced Deposition (FEBID) for magnetic tip fabrication is presented in this work as an alternative to conventional sputtering-based Magnetic Force Microscopy (MFM) tips. FEBID enables the growth of a high-aspect-ratio magnetic nanorod… read more here.
Keywords: probes based; based magnetic; customized mfm; mfm probes ... See more keywords
Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d1cs00307k
Abstract: The discovery of a near-infrared (NIR, 650-900 nm) fluorescent chromophore hemicyanine dye with high structural tailorability is of great significance in the field of detection, bioimaging, and medical therapeutic applications. It exhibits many outstanding advantages… read more here.
Keywords: fluorescent; probes based; hemicyanine; activity based ... See more keywords
Near-infrared fluorescence probes based on disassembly-induced emission pyrene derivatives
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Materials Chemistry C"
DOI: 10.1039/d3tc03292b
Abstract: Organic near–infrared dyes are commonly used for bioimaging due to their low photodamage and high penetration depth into biological tissue. Pyrene is an aromatic compound with a large π–conjugation and... read more here.
Keywords: pyrene; based disassembly; infrared fluorescence; probes based ... See more keywords
Affinity probes based on small-molecule inhibitors for tumor imaging
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1028493
Abstract: Methods for molecular imaging of target areas, including optical imaging, radionuclide imaging, magnetic resonance imaging and other imaging technologies, are helpful for the early diagnosis and precise treatment of cancers. In addition to cancer management,… read more here.
Keywords: molecule inhibitors; small molecule; affinity; probes based ... See more keywords