Novel lipid tools and probes for biological investigations.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2018.06.013
Abstract: We present the latest advances in lipid tool development for studying cellular membrane trafficking and metabolism. We focus on chemical modifications that are introduced to natural lipid structures. The new functionalities are used to follow… read more here.
Keywords: probes biological; novel lipid; lipid tools; tools probes ... See more keywords
Validating Small Molecule Chemical Probes for Biological Discovery.
Sign Up to like & getrecommendations! Published in 2022 at "Annual review of biochemistry"
DOI: 10.1146/annurev-biochem-032620-105344
Abstract: Small molecule chemical probes are valuable tools for interrogating protein biological functions and relevance as a therapeutic target. Rigorous validation of chemical probe parameters such as cellular potency and selectivity is critical to unequivocally linking… read more here.
Keywords: small molecule; chemical probes; molecule chemical; chemical ... See more keywords