Probing the Electrostatic and Steric Requirements for Substrate Binding in Human Platelet-Type 12-Lipoxygenase.
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DOI: 10.1021/acs.biochem.8b01167
Abstract: Human platelet ALOX12 (hALOX12 or h12-LOX) has been implicated in a variety of human diseases. The present study investigates the active site of hALOX12 to more thoroughly understand how it positions the substrate and achieves… read more here.
Keywords: substrate binding; probing electrostatic; active site; site ... See more keywords