Probing the orientation of inhibitor and epoxy-eicosatrienoic acid binding in the active site of soluble epoxide hydrolase.
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DOI: 10.1016/j.abb.2016.10.017
Abstract: Soluble epoxide hydrolase (sEH) is an important therapeutic target of many diseases, such as chronic obstructive pulmonary disease (COPD) and diabetic neuropathic pain. It acts by hydrolyzing and thus regulating specific bioactive long chain polyunsaturated… read more here.
Keywords: soluble epoxide; orientation; epoxide hydrolase; probing orientation ... See more keywords