Boundary problem in Simon’s two-stage clinical trial designs
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DOI: 10.1080/10543406.2016.1148716
Abstract: ABSTRACT The activity of a new treatment in clinical trials with binary endpoints can be assessed by comparing the observed response rate to the target response rate. Traditionally, a one-sided hypothesis is used to make… read more here.
Keywords: problem simon; two stage; property; boundary problem ... See more keywords