Prediction of Protein and RNA Structures by Co-Evolution: Going Beyond Anecdotal Cases towards Large-Scale
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DOI: 10.1016/j.bpj.2016.11.326
Abstract: Structural characterization of many important proteins and protein complexes - typically preceding any detailed mechanistic exploration of their function- remains experimentally challenging. Novel statistical tools such as Direct Coupling Analysis (DCA) take advantage of the… read more here.
Keywords: large scale; proc nat; nat acad; beyond anecdotal ... See more keywords