Procaine is a specific DNA methylation inhibitor with anti‐tumor effect for human gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26407
Abstract: DNA hypermethylation and the silencing of tumor suppressor genes caused by DNA hypermethylation is considered as a molecular hallmark of many kinds of cancers. Procaine, a local anesthetic, has been shown as a potential DNA… read more here.
Keywords: gastric cancer; procaine; dna methylation; dna ... See more keywords
Deciphering the interaction of procaine with bovine serum albumin and elucidation of binding site: A multi spectroscopic and molecular docking study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2017.04.020
Abstract: Abstract The mechanism of interaction between anesthetic drug procaine with model serum protein bovine serum albumin (BSA) was seen by means of various spectroscopic and molecular docking methods. The spectroscopic techniques used in the study… read more here.
Keywords: bsa; molecular docking; site; procaine ... See more keywords
Comparison of Lidocaine-Xylazine and Procaine-Xylazine for Lumbar Epidural Anesthesia in Cattle
Sign Up to like & getrecommendations! Published in 2019 at "Journal of the Hellenic Veterinary Medical Society"
DOI: 10.12681/jhvms.21802
Abstract: Lumbar epidural anesthesia is commonly utilized in veterinary medicine for diagnostic, obstetrical, and surgical intervention in the abdominal and perineal regions of large animals. The aim of this study was to directly compare the time… read more here.
Keywords: procaine xylazine; procaine; xylazine procaine; lidocaine xylazine ... See more keywords
Procaine Regulates the STAT3/CCL5 Axis and Inhibits Microglia M1 Polarization to Alleviate Complete Freund’s Adjuvant Rats Pain Behavior
Sign Up to like & getrecommendations! Published in 2024 at "eNeuro"
DOI: 10.1523/eneuro.0303-24.2024
Abstract: Neuropathic pain (NP) caused by sciatic nerve injury can significantly impact the quality of life of patients. The M1 phenotype of microglia has been reported to promote the progression of NP. Procaine is a lipid-soluble… read more here.
Keywords: ccl5 axis; procaine; microglia polarization; polarization ... See more keywords