Human procaspase-2 phosphorylation at both S139 and S164 is required for 14-3-3 binding.
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DOI: 10.1016/j.bbrc.2017.09.116
Abstract: Procaspase-2 phosphorylation at several residues prevents its activation and blocks apoptosis. This process involves procaspase-2 phosphorylation at S164 and its binding to the scaffolding protein 14-3-3. However, bioinformatics analysis has suggested that a second phosphoserine-containing… read more here.
Keywords: required binding; phosphorylation; s164; procaspase phosphorylation ... See more keywords