Use of ultrafiltration/diafiltration for the processing of antisense oligonucleotides.
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DOI: 10.1002/btpr.3350
Abstract: Ultrafiltration/diafiltration (UF/DF) has been the hallmark for concentrating and buffer exchange of protein and peptide-based therapeutics for years. Here we examine the capabilities and limitations of UF/DF membranes to process oligonucleotides using antisense oligonucleotides (ASOs)… read more here.
Keywords: diafiltration; use ultrafiltration; antisense oligonucleotides; processing antisense ... See more keywords