Aberrant antigen processing and presentation: Key pathogenic factors leading to immune activation in Ankylosing spondylitis.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in immunopathology"
DOI: 10.1007/s00281-020-00833-w
Abstract: The strong association of HLA-B*27 with ankylosing spondylitis (AS) was first reported nearly 50 years ago. However, the mechanistic link between HLA-B*27 and AS has remained an enigma. While 85-90% of AS patients possess HLA-B*27,… read more here.
Keywords: processing presentation; antigen processing; ankylosing spondylitis; hla ... See more keywords
Antigen processing and presentation.
Sign Up to like & getrecommendations! Published in 2019 at "International review of cell and molecular biology"
DOI: 10.1016/bs.ircmb.2019.07.005
Abstract: Dendritic cells are at the center of immune responses. They are defined by their ability to sense the environment, take up and process antigen, migrate to secondary lymphoid organs, where they present antigens to the… read more here.
Keywords: processing presentation; antigen processing; antigen; biology ... See more keywords
Antigen processing and presentation in cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2020 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-001111
Abstract: Background Knowledge about and identification of T cell tumor antigens may inform the development of T cell receptor-engineered adoptive cell transfer or personalized cancer vaccine immunotherapy. Here, we review antigen processing and presentation and discuss… read more here.
Keywords: cancer; processing presentation; cell; antigen processing ... See more keywords
Maintenance of Hypoimmunogenic Features via Regulation of Endogenous Antigen Processing and Presentation Machinery
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.936584
Abstract: Universally acceptable donor cells have been developed to address the unmet need for immunotypically matched materials for regenerative medicine. Since forced expression of hypoimmunogenic genes represses the immune response, we established universal pluripotent stem cells… read more here.
Keywords: presentation machinery; processing presentation; presentation; hla ... See more keywords
Targeting the antigen processing and presentation pathway to overcome resistance to immune checkpoint therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.948297
Abstract: Despite the significant clinical advances with the use of immune checkpoint inhibitors (ICIs) in a wide range of cancer patients, response rates to the therapy are variable and do not always result in long-term tumor… read more here.
Keywords: processing presentation; immune checkpoint; antigen processing; therapy ... See more keywords
Editorial: alternative antigen processing and presentation in immune disorders
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.993393
Abstract: COPYRIGHT © 2022 Alvarez, Antón and James. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided… read more here.
Keywords: presentation immune; processing presentation; alternative antigen; antigen processing ... See more keywords
Sublethal Radiation Affects Antigen Processing and Presentation Genes to Enhance Immunogenicity of Cancer Cells
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21072573
Abstract: While immunotherapy in cancer is designed to stimulate effector T cell response, tumor-associated antigens have to be presented on malignant cells at a sufficient level for recognition of cancer by T cells. Recent studies suggest… read more here.
Keywords: antigen processing; processing presentation; cancer cells; cancer ... See more keywords