SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts.
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DOI: 10.1016/j.molcel.2020.05.011
Abstract: Many microRNAs (miRNAs) are generated from primary transcripts containing multiple clustered stem-loop structures that are thought to be recognized and cleaved by the Microprocessor complex as independent units. Here, we uncover an unexpected mode of… read more here.
Keywords: mirna; processing suboptimal; loop structures; stem loop ... See more keywords