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   Articles with "processivity" as a keyword



Kinesin Processivity Is Determined by a Kinetic Race from a Vulnerable One-Head-Bound State.

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recommendations! Published in 2017 at "Biophysical journal"

DOI: 10.1016/j.bpj.2017.05.007

Abstract: Kinesin processivity, defined as the average number of steps that occur per interaction with a microtubule, is an important biophysical determinant of the motor's intracellular capabilities. Despite its fundamental importance to the diversity of tasks… read more here.

Keywords: head; kinesin processivity; state; one head ... See more keywords
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Engineering Transcriptional Interference through RNA Polymerase Processivity Control.

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recommendations! Published in 2021 at "ACS synthetic biology"

DOI: 10.1021/acssynbio.0c00534

Abstract: Antisense transcription is widespread in all kingdoms of life and has been shown to influence gene expression through transcriptional interference (TI), a phenomenon in which one transcriptional process negatively influences another in cis. The processivity,… read more here.

Keywords: transcriptional interference; biology; processivity; processivity control ... See more keywords

Processivity and specificity of histone acetylation by the male-specific lethal complex

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recommendations! Published in 2024 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkae123

Abstract: Abstract Acetylation of lysine 16 of histone H4 (H4K16ac) stands out among the histone modifications, because it decompacts the chromatin fiber. The metazoan acetyltransferase MOF (KAT8) regulates transcription through H4K16 acetylation. Antibody-based studies had yielded… read more here.

Keywords: specific lethal; processivity; male specific; acetylation ... See more keywords

Limited processivity of single motors improves overall transport flux of self-assembled motor-cargo complexes.

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recommendations! Published in 2019 at "Physical review. E"

DOI: 10.1103/physreve.100.022408

Abstract: Single kinesin molecular motors can processively move along a microtubule (MT) a few micrometers on average before dissociating. However, cellular length scales over which transport occurs are several hundred microns and more. Why seemingly unreliable… read more here.

Keywords: transport; cargo; processivity; motor ... See more keywords

GGCX mutants that impair hemostasis reveal the importance of processivity and full carboxylation to VKD protein function.

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recommendations! Published in 2022 at "Blood"

DOI: 10.1182/blood.2021014275

Abstract: The gamma-glutamyl carboxylase (GGCX) generates multiple carboxylated Glus (Glas) in vitamin K-dependent (VKD) proteins that are required for their functions. GGCX is processive, remaining bound to VKD proteins throughout the multiple Glu carboxylations, and this… read more here.

Keywords: vkd protein; vkd; carboxylation; processivity ... See more keywords

The Arabidopsis kinesin-4, FRA1, requires a high level of processive motility to function correctly

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recommendations! Published in 2017 at "Journal of Cell Science"

DOI: 10.1242/jcs.196857

Abstract: ABSTRACT Processivity is important for kinesins that mediate intracellular transport. Structure–function analyses of N-terminal kinesins (i.e. kinesins comprising their motor domains at the N-terminus) have identified several non-motor regions that affect processivity in vitro. However,… read more here.

Keywords: processive motility; processivity; function; kinesin ... See more keywords