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   Articles with "procollagen" as a keyword



ER, Mitochondria, and ISR Regulation by mt‐HSP70 and ATF5 upon Procollagen Misfolding in Osteoblasts

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recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202201273

Abstract: Cellular response to protein misfolding underlies multiple diseases. Collagens are the most abundant vertebrate proteins, yet little is known about cellular response to misfolding of their procollagen precursors. Osteoblasts (OBs)—the cells that make bone—produce so… read more here.

Keywords: procollagen misfolding; hsp70 atf5; procollagen; response ... See more keywords

Ascorbate starvation alters endoplasmic reticulum-resident enzymes in cardiac fibroblasts, priming them for increased procollagen secretion.

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recommendations! Published in 2017 at "Journal of molecular and cellular cardiology"

DOI: 10.1016/j.yjmcc.2017.09.005

Abstract: Since ascorbate is unnecessary for cell growth and survival, cardiac fibroblasts are routinely cultured without it. However, ascorbate is necessary for optimal collagen synthesis, so we hypothesized that its presence would influence cell phenotype. Cardiac… read more here.

Keywords: ascorbate; secretion; endoplasmic reticulum; cardiac fibroblasts ... See more keywords

Deficiency of Procollagen C-Proteinase Enhancer 1 in Mice has No Major Impact on Cardiac Collagen and Function Under Basal Conditions

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recommendations! Published in 2021 at "Journal of Cardiovascular Pharmacology"

DOI: 10.1097/fjc.0000000000001122

Abstract: Supplemental Digital Content is Available in the Text. Abstract: Maturation of fibrillar collagen is known to play a crucial role in the pathophysiology of myocardial fibrosis. Procollagen C-proteinase enhancer 1 (PCPE1) has a key role… read more here.

Keywords: procollagen; mice; cardiac collagen; collagen ... See more keywords

1-Kestose Blocks UVB-Induced Skin Inflammation and Promotes Type I Procollagen Synthesis via Regulating MAPK/AP-1, NF-κB and TGF-β/Smad Pathway

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recommendations! Published in 2024 at "Journal of Microbiology and Biotechnology"

DOI: 10.4014/jmb.2311.11020

Abstract: Solar UVB irradiation cause skin photoaging by inducing the high expression of matrix metalloproteinase (MMPs) to inhibit the expression of Type1 procollagen synthesis. 1-Kestose, a natural trisaccharide, has been indicated to show a cytoprotective role… read more here.

Keywords: tgf smad; procollagen; procollagen synthesis; skin ... See more keywords

Serum type III procollagen, procollagen V, tumour necrosis factor-a, interleukin-6 in liver cirrhosis after antiviral treatment

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recommendations! Published in 2025 at "Journal of Medical Biochemistry"

DOI: 10.5937/jomb0-56353

Abstract: Background To evaluate the therapeutic effects of entecavir combined with reduced glutathione on serum type III procollagen (PCIII), plasma procollagen V (IVC), Tumour Necrosis Factor-a (TNF-a), interleukin-6 (IL-6), and nutritional status in patients with hepatitis… read more here.

Keywords: treatment; procollagen; group; serum type ... See more keywords