Anti‐myocardial Ischemia Effect and Components of Litchi Pericarp Extracts
Sign Up to like & getrecommendations! Published in 2017 at "Phytotherapy Research"
DOI: 10.1002/ptr.5865
Abstract: Litchi (Litchi chinensis Sonn.) is a famous fruit in south China, and it is also effective for chest tightness or chest pain, irritability, flatulence, epigastric pain and neuralgic pain, hernia pain and testicular swelling, cough,… read more here.
Keywords: litchi pericarp; myocardial ischemia; pain; effect ... See more keywords
Procyanidin B1, a novel and specific inhibitor of Kv10.1 channel, suppresses the evolution of hepatoma.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2020.114089
Abstract: Recently, we and other groups revealed that aberrant expression of Kv10.1 channel, a voltage-gated potassium ion channel, contributes to a variety of tumorigenesis process.Potent and selective inhibitor of Kv10.1 is urgently needed, both as pharmacological… read more here.
Keywords: kv10 channel; inhibitor; channel; procyanidin ... See more keywords
Distribution of crown hexameric procyanidin and its tetrameric and pentameric congeners in red and white wines.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.125125
Abstract: Nineteen red and white wines were screened for the presence of crown (oligomeric cyclic) procyanidins with 4, 5 or 6 (epi)catechin monomers by means of HPLC-HRMS/MS. For the first time, the distribution of crown procyanidins… read more here.
Keywords: red white; distribution crown; white wines; crown hexameric ... See more keywords
Procyanidin B2 ameliorates endothelial dysfunction and impaired angiogenesis via the Nrf2/PPARγ/sFlt-1 axis in preeclampsia.
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacological research"
DOI: 10.1016/j.phrs.2022.106127
Abstract: Preeclampsia is a severe complication of pregnancy characterized by variable degrees of placental malperfusion. A growing body of evidence indicates that soluble endoglin and soluble fms-like tyrosine kinase-1 (sFlt-1) play important pathophysiological roles in preeclampsia,… read more here.
Keywords: angiogenesis; endothelial dysfunction; procyanidin; preeclampsia ... See more keywords
Procyanidin B2 mitigates endothelial endoplasmic reticulum stress through a PPARδ-Dependent mechanism
Sign Up to like & getrecommendations! Published in 2020 at "Redox Biology"
DOI: 10.1016/j.redox.2020.101728
Abstract: Hyperglycemia-induced endothelial endoplasmic reticulum (ER) stress is implicated in the pathophysiology of diabetes and its vascular complications. Procyanidins are enriched in many plant foods and have been demonstrated to exert several beneficial effects on diabetes,… read more here.
Keywords: ppar; endoplasmic reticulum; endothelial endoplasmic; reticulum stress ... See more keywords
Integrated Utilization of Red Radish for the Efficient Production of High-Purity Procyanidin Dimers.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.8b02478
Abstract: Red radish was extracted by methanol to obtain crude radish procyanidin extracts. The purity of procyanidin (PP) and procyanidin dimers (PD) of crude radish procyanidin extracts under different ratios of methanol to radish was optimized… read more here.
Keywords: radish procyanidin; red radish; procyanidin dimers; purity procyanidin ... See more keywords
Coordination of AMPK and YAP by Spatholobi Caulis and Procyanidin B2 Provides Antioxidant Effects In Vitro and In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213730
Abstract: The liver is vulnerable to oxidative attacks from heavy metals, such as iron, as well as some drugs, including acetaminophen. It has been shown that enhanced oxidative stress in the liver leads to excessive ROS… read more here.
Keywords: vitro vivo; antioxidant effects; procyanidin; spatholobi caulis ... See more keywords
Procyanidin C1 Location, Interaction, and Aggregation in Two Complex Biomembranes
Sign Up to like & getrecommendations! Published in 2022 at "Membranes"
DOI: 10.3390/membranes12070692
Abstract: Procyanidins are known for their many benefits to human health and show a plethora of biological effects. One of the most important procyanidin is the procyanidin trimer C1 (PC1). Due to its relatively high lipid–water… read more here.
Keywords: procyanidin; pc1; interaction aggregation; membrane ... See more keywords
Analysis of Commercial Proanthocyanidins. Part 6: Sulfitation of Flavan-3-Ols Catechin and Epicatechin, and Procyanidin B-3
Sign Up to like & getrecommendations! Published in 2020 at "Molecules"
DOI: 10.3390/molecules25214980
Abstract: Proanthocyanidins (PACs) are natural plant-derived polymers consisting of flavan-3-ol monomers. Quebracho (Schinopsis lorentzii and balansae) heartwood and mimosa (Acacia mearnsii) bark extracts are the major industrial sources of PACs. These commercial extracts are often sulfited… read more here.
Keywords: catechin epicatechin; flavan ols; flavan; ols catechin ... See more keywords
The Relationship between Procyanidin Structure and Their Protective Effect in a Parkinson’s Disease Model
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27155007
Abstract: This study evaluated the effect of grape seed-derived monomer, dimeric, and trimeric procyanidins on rat pheochromocytoma cell line (PC12) cells and in a zebrafish Parkinson’s disease (PD) model. PC12 cells were cultured with grape seed-derived… read more here.
Keywords: procyanidin; effect; parkinson disease; pc12 cells ... See more keywords
Effect of Procyanidin on Canine Sperm Quality during Chilled Storage
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Sciences"
DOI: 10.3390/vetsci9110588
Abstract: Simple Summary In recent years, artificial insemination (AI) using chilled sperm has been one of the most utilized artificial assisted reproductive technologies for dogs. However, changes in temperature can cause oxidative stress, damage sperm structure,… read more here.
Keywords: sperm quality; procyanidin; canine sperm; quality ... See more keywords