Performance of the Movement Disorders Society criteria for prodromal Parkinson's disease: A population‐based 10‐year study
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DOI: 10.1002/mds.27281
Abstract: Objective: We aimed to identify prodromal Parkinson's disease (PD) and its predictive accuracy for incident PD in an unselected elderly population and to estimate the relevance of this approach for future neuroprotection trials. read more here.
Keywords: prodromal parkinson; population; movement disorders; parkinson disease ... See more keywords
Update of the MDS research criteria for prodromal Parkinson's disease
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DOI: 10.1002/mds.27802
Abstract: The MDS Research Criteria for Prodromal PD allow the diagnosis of prodromal Parkinson's disease using an evidence‐based conceptual framework, which was designed to be updated as new evidence becomes available. New prospective evidence of predictive… read more here.
Keywords: parkinson; research criteria; prodromal parkinson; parkinson disease ... See more keywords
Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson's Disease Reveals Distinct Metabolic Profiles.
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DOI: 10.1021/acs.jproteome.8b00224
Abstract: Parkinson's disease is the second most common neurodegenerative disease. In the vast majority of cases the origin is not genetic and the cause is not well understood, although progressive accumulation of α-synuclein aggregates appears central… read more here.
Keywords: model prodromal; disease; prodromal parkinson; parkinson disease ... See more keywords
Mediterranean diet is associated with a lower probability of prodromal Parkinson's disease and risk for Parkinson's disease/dementia with Lewy bodies: A longitudinal study
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DOI: 10.1111/ene.15698
Abstract: Lifestyle factors have been implicated in the long‐lasting neurodegenerative process in prodromal Parkinson's disease (pPD). The aim was to investigate the associations between adherence to a Mediterranean diet (MeDi) and longitudinal changes of pPD probability… read more here.
Keywords: prodromal parkinson; parkinson disease; mediterranean diet; parkinson ... See more keywords
Statistical Considerations in the Design of Clinical Trials Targeting Prodromal Parkinson Disease
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DOI: 10.1212/wnl.0000000000200897
Abstract: Clinical trials testing interventions for prodromal Parkinson disease (PD) hold particular promise for preserving neuronal function and thereby slowing or even forestalling progression to overt PD. Selection of the appropriate target population and outcome measures… read more here.
Keywords: outcome; clinical trials; prodromal parkinson; parkinson disease ... See more keywords