Articles with "prodrug cklp1" as a keyword



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Pharmacological and pharmacokinetic profile of the novel ocular hypotensive prodrug CKLP1 in Dutch-belted pigmented rabbits

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Published in 2020 at "PLoS ONE"

DOI: 10.1371/journal.pone.0231841

Abstract: Elevated intraocular pressure is the only treatable risk factor for glaucoma, an eye disease that is the leading cause of irreversible blindness worldwide. We have identified cromakalim prodrug 1 (CKLP1), a novel water-soluble ATP-sensitive potassium… read more here.

Keywords: cklp1; ocular hypotensive; prodrug cklp1; belted pigmented ... See more keywords