An exosome-like programmable-bioactivating paclitaxel prodrug nanoplatform for enhanced breast cancer metastasis inhibition.
Sign Up to like & getrecommendations! Published in 2020 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2020.120224
Abstract: Metastasis is closely associated with high breast cancer mortality. Although nanotechnology-based anti-metastatic treatments have developed rapidly, the anti-metastasis efficiency is still far from satisfactory, mainly due to the poor recognition of circulating tumor cells (CTCs)… read more here.
Keywords: prodrug nanoplatform; inhibition; metastasis; cancer ... See more keywords
Engineering Polymeric Prodrug Nanoplatform for Vaccination Immunotherapy of Cancer.
Sign Up to like & getrecommendations! Published in 2020 at "Nano letters"
DOI: 10.1021/acs.nanolett.0c01140
Abstract: Neoantigen-based cancer vaccines are promising for boosting cytotoxic T lymphocytes (CTLs) responses. However, the therapeutic effect of cancer vaccines is severely blunted by functional suppression of the dendritic cells (DCs). Herein, we demonstrated an acid-responsive… read more here.
Keywords: prodrug nanoplatform; immunotherapy; polymeric prodrug; cancer ... See more keywords