Development of Fluorophosphoramidate as a Biocompatibly Transformable Functional Group and its Application as a Phosphate Prodrug for Nucleoside Analogs
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DOI: 10.1002/cmdc.202200188
Abstract: Synthetic phosphate‐derived functional groups are important for controlling the function of bioactive molecules in vivo. Herein we describe the development of a new type of biocompatible phosphate analog, a fluorophosphoramidate (FPA) functional group that has characteristic… read more here.
Keywords: prodrug nucleoside; group; amino group; nucleoside analogs ... See more keywords