Triphosphate Prodrugs of the Anti-HIV-Active Compound 3'-Deoxy-3'-fluorothymidine (FLT).
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DOI: 10.1021/acs.jmedchem.2c00665
Abstract: 3'-Fluoro-3'-deoxythymidine (FLT) was identified as one of the most potent inhibitors of human immunodeficiency virus (HIV) replication. However, FLT also showed severe toxicity so that it was abundant as a potential chemotherapeutic agent. Here, we… read more here.
Keywords: triphosphate prodrugs; flt; hiv active; prodrugs anti ... See more keywords