6-Thioguanosine Monophosphate Prodrugs Display Enhanced Performance against Thiopurine-Resistant Leukemia and Breast Cancer Cells
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DOI: 10.1021/acs.jmedchem.2c01010
Abstract: Thiopurines are in widespread clinical use for the treatment of immunological disorders and certain cancers. However, treatment failure due to resistance or adverse drug reactions are common, asking for new therapeutic strategies. We investigated the… read more here.
Keywords: monophosphate prodrugs; 6sgmp prodrugs; prodrugs display; thioguanosine monophosphate ... See more keywords