Synthesis and biological evaluation of N-alkyl-1,4-dihydroquinoline prodrugs of scutellarin methyl ester as neuroprotective agents
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DOI: 10.1007/s00044-018-2134-8
Abstract: A series of N-alkyl-1,4-dihydroquinoline prodrugs of scutellarin methyl ester have been synthesized (4a–4f). Compared to the parent compound scutellarin, we demonstrated that these prepared compounds had higher water solubility, more appropriate logP and better stability.… read more here.
Keywords: prodrugs scutellarin; alkyl dihydroquinoline; methyl ester; synthesis biological ... See more keywords