Si113-prodrugs selectively activated by plasmin against hepatocellular and ovarian carcinoma.
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DOI: 10.1016/j.ejmech.2021.113653
Abstract: Si113, a pyrazolo[3,4-d]pyrimidine derivative, gained more attention as an anticancer agent due to its potent anticancer activity on both in vitro and in vivo hepatocellular carcinomas (HCC) and ovarian carcinoma models. But the drawback is the low… read more here.
Keywords: hcc; carcinoma; si113 prodrugs; prodrugs selectively ... See more keywords