Co‐microencapsulation of human umbilical cord‐derived mesenchymal stem and pancreatic islet‐derived insulin producing cells in experimental type 1 diabetes
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes/Metabolism Research and Reviews"
DOI: 10.1002/dmrr.3372
Abstract: Post‐partum umbilical cord Wharton Jelly‐derived adult mesenchymal stem cells (hUCMS) hold anti‐inflammatory and immunosuppressive properties. Human pancreatic islet‐derived progenitor cells (hIDC) may de‐differentiate, and subsequently re‐differentiate into insulin producing cells. The two cell types share… read more here.
Keywords: pancreatic islet; umbilical cord; producing cells; islet derived ... See more keywords
GATA factors in pancreas development and disease
Sign Up to like & getrecommendations! Published in 2019 at "IUBMB Life"
DOI: 10.1002/iub.2170
Abstract: There is an urgent need for the development of novel therapeutics options for diabetic patients given the high prevalence of diabetes worldwide and that, currently, there is no cure for this disease. The transplantation of… read more here.
Keywords: producing cells; pancreas development; disease; factors pancreas ... See more keywords
Generation of Functional Insulin-Producing Cells from Mouse Embryonic Stem Cells Through Protein Transduction of Transcription Factors.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0943-9_7
Abstract: In this chapter, we describe a simple and unique method for the differentiation of mouse embryonic stem cells into insulin-producing cells. In addition to cytokines and growth factors, key transcription factors for pancreatic development are… read more here.
Keywords: transcription factors; producing cells; mouse embryonic; embryonic stem ... See more keywords
Impact of cardiac resynchronization therapy on circulating IL-17 producing cells in patients with advanced heart failure
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Interventional Cardiac Electrophysiology"
DOI: 10.1007/s10840-018-0491-3
Abstract: PurposeIL-17-producing T cells have been implicated in the inflammatory milieu of chronic heart failure (CHF), which implies a dismal prognosis in affected patients. The aim of this study was to evaluate the impact of cardiac… read more here.
Keywords: impact cardiac; tc17 cells; producing cells; heart failure ... See more keywords
Vector-free in vivo trans-determination of adult hepatic stem cells to insulin-producing cells
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Biology Reports"
DOI: 10.1007/s11033-019-04870-z
Abstract: A reduction in the number of functional β-cells is the central pathological event in diabetes. Liver and ventral pancreas differentiates simultaneously in the same general domain of cells within embryonic endoderm. In addition, the precursor… read more here.
Keywords: vector free; hepatic stem; producing cells; stem ... See more keywords
Transplantation of Macroencapsulated Insulin-Producing Cells
Sign Up to like & getrecommendations! Published in 2018 at "Current Diabetes Reports"
DOI: 10.1007/s11892-018-1028-y
Abstract: Purpose of ReviewThere is considerable interest in using macroencapsulation devices as a delivery strategy for transplanting insulin-producing cells. This review aims to summarize recent advances, to highlight remaining challenges, and to provide recommendations for the… read more here.
Keywords: insulin; macroencapsulated insulin; producing cells; beta ... See more keywords
Granzyme B producing B-cells in renal transplant patients.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.04.016
Abstract: OBJECTIVES A separate subset of Granzyme B (GrB) producing B-cells regulating T-cell mediated immunity has been identified. In the present study, we investigated the role of GrB+ B-cells in renal transplant patients (RTX). METHODS 12… read more here.
Keywords: transplant patients; producing cells; grb; cells renal ... See more keywords
Aberrant frequency of IL‐35 producing B cells in colorectal cancer patients
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2017.10.011
Abstract: Background The IL‐10 dependent regulatory function of B cells had recently more and more investigated and play important roles in cancer immunity, however, beyond IL‐10 whether other inhibitory cytokines play an important role in cancer… read more here.
Keywords: producing cells; frequency; colorectal cancer; cells colorectal ... See more keywords
The role of IL-10-producing B cells in Repeated Implantation Failure patients with cellular immune abnormalities.
Sign Up to like & getrecommendations! Published in 2019 at "Immunology letters"
DOI: 10.1016/j.imlet.2019.08.002
Abstract: There are a few data of the role of B cells in RIF pathogenesis. Accordingly, the objective of the current study was to determine the role of IL-10-producing B cells in RIF. Twenty-three RIF women… read more here.
Keywords: role producing; producing cells; immune abnormalities; cells repeated ... See more keywords
Skin IL-17-Producing T Cells Support Repair 2!
Sign Up to like & getrecommendations! Published in 2019 at "Trends in immunology"
DOI: 10.1016/j.it.2019.01.004
Abstract: In a recent study, Harrison et al. (Science 2019;363;eaat6280) report that RORγt-expressing skin commensal-specific T cells rapidly respond to tissue wounding by producing type 2 T helper cell (Th2) cytokines in mice. The cells constitutively… read more here.
Keywords: producing cells; cells support; support repair; repair ... See more keywords
Short-chain fatty acid butyrate induces IL-10-producing B cells by regulating circadian-clock-related genes to ameliorate Sjögren's syndrome.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2021.102611
Abstract: OBJECTIVES Sjögren's syndrome (SS) is an autoimmune disease caused by inflammation of the exocrine gland. The pathological hallmark of SS is the infiltration of lymphocytes into the salivary glands. Increased infiltration of T and B… read more here.
Keywords: clock related; gren syndrome; butyrate; producing cells ... See more keywords