Epidemiology and antimicrobial susceptibility profiles of extended-spectrum beta-lactamase–producing Klebsiella pneumoniae and Escherichiacoli in China
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DOI: 10.1007/s42770-019-00081-7
Abstract: ObjectsThe retrospective study aimed to determine the prevalence rate and antimicrobial susceptibility of extended-spectrum beta-lactamases (ESBLs)–producing Klebsiella pneumoniae and Escherichia coli in 2013–2017 at a single center in China.MethodsKlebsiella pneumoniae and Escherichia coli data were… read more here.
Keywords: esbls producing; escherichia coli; producing klebsiella; epidemiology ... See more keywords
Outbreak of NDM-1-producing Klebsiella pneumoniae in the intensive care unit during the COVID-19 pandemic: Another nightmare
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DOI: 10.1016/j.ajic.2021.07.004
Abstract: An outbreak of Klebsiella pneumoniae producing the carbapenemase NDM-1 occurred in our ICU during the last COVID-19 wave. Twelve patients were tested positive, seven remained asymptomatic whereas five developed an infection. Resistome and in silico… read more here.
Keywords: outbreak ndm; klebsiella; producing klebsiella; ndm producing ... See more keywords
Multidrug-resistant CTX-M-15-producing Klebsiella pneumoniae ST231 associated with infection and persistent colonization of dog.
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DOI: 10.1016/j.diagmicrobio.2018.06.012
Abstract: Extended spectrum β-lactamase (ESBL)-producing bacterial infections in veterinary medicine are a clinical and epidemiological challenge. We report a case of CTX-M-15-producing Klebsiella pneumoniae infection followed by persistent colonization, in a dog presenting with bilateral purulent… read more here.
Keywords: ctx producing; producing klebsiella; infection; pneumoniae ... See more keywords
Carbapenemase-producing Klebsiella pneumoniae intra-abdominal infection successfully treated with ceftazidime/avibactam plus tigecycline
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DOI: 10.1016/j.idcr.2020.e00745
Abstract: Ceftazidime/avibactam combines ceftazidime with a new beta-lactam that successfully that inhibits Amber Class A and D carbapenemases. We report a clinical case of a 61 year-old man with a carbapenemase-producing Klebsiella pneumoniae intra-abdominal infection after… read more here.
Keywords: ceftazidime avibactam; carbapenemase producing; pneumoniae intra; producing klebsiella ... See more keywords
Carbapenemase producing Klebsiella pneumoniae (KPC) meningitis from chronic otitis media
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DOI: 10.1016/j.idcr.2020.e00963
Abstract: Meningitis and brain abscess caused by carbapenemase-producing Klebsiella pneumoniae (KPC) is rarely described in the medical literature. Such infections have been described after neurosurgical medium or post-trauma. We describe an unusual case of KPC meningitis… read more here.
Keywords: meningitis; carbapenemase producing; pneumoniae kpc; producing klebsiella ... See more keywords
Genomic analysis of the first isolate of KPC-2-producing Klebsiella pneumoniae from Uruguay.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2018.09.001
Abstract: OBJECTIVES Since KPC-2-producing Klebsiella pneumoniae are associated with successful dissemination of a major clone, defined as sequence type 258 (ST258), the aim of this study was to perform whole-genome sequencing (WGS) of the first colistin-resistant… read more here.
Keywords: producing klebsiella; analysis; pneumoniae; first isolate ... See more keywords
Proof‑of‑concept study to quantify changes in intestinal loads of KPC-producing Klebsiella pneumoniae in colonized patients following selective digestive decontamination with oral gentamicin.
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DOI: 10.1016/j.jgar.2022.04.010
Abstract: OBJECTIVES To monitor quantitatively the extent of intestinal colonization by KPC-producing Klebsiella pneumoniae (KPC-Kp) in colonized patients who receive selective digestive decontamination (SDD) with oral gentamicin. METHODS We developed a real-time quantitative PCR (qPCR) method for… read more here.
Keywords: kpc producing; producing klebsiella; gentamicin; colonized patients ... See more keywords
Spread of OXA-48-producing Klebsiella pneumoniae among COVID-19-infected patients: The storm after the storm
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DOI: 10.1016/j.jiph.2020.11.001
Abstract: The impact of secondary infections by multidrug-resistant bacteria in COVID-19- infected patients has yet to be evaluated. Here, we report the clinical and molecular features of an outbreak of seven patients carrying CTX-M-15- and OXA-48-producing… read more here.
Keywords: producing klebsiella; covid infected; infected patients; klebsiella pneumoniae ... See more keywords
Antimicrobial activity and mode of action of 1,8-cineol against carbapenemase-producing Klebsiella pneumoniae
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DOI: 10.1038/s41598-021-00249-y
Abstract: Antimicrobial resistance remains one of the most challenging issues that threatens the health of people around the world. Plant-derived natural compounds have received considerable attention for their potential role to mitigate antibiotic resistance. This study… read more here.
Keywords: carbapenemase producing; producing klebsiella; antimicrobial activity; mode action ... See more keywords
Epidemiology of Carbapenemase-Producing Klebsiella pneumoniae in a Portuguese Tertiary Hospital
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DOI: 10.1093/eurpub/ckaa166.725
Abstract: Carbapenemase-producing Klebsiella pneumoniae (CPKp) are considered a public health problem. To manage this multidrug-resistant organism (MDRO), it is important to identify individuals at higher risk. We describe risk factors for CPKp among a population who… read more here.
Keywords: carbapenemase producing; producing klebsiella; hospital; epidemiology ... See more keywords
Pharmacodynamics of colistin resistance in carbapenemase-producing Klebsiella pneumoniae: the double-edged sword of heteroresistance and adaptive resistance.
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DOI: 10.1099/jmm.0.001565
Abstract: Introduction. The presence of heteroresistant subpopulations and the development of resistance during drug exposure (adaptive resistance) limits colistin's efficacy against carbapenemase-producing Klebsiella pneumoniae (CP-Kp) isolates.Hypothesis/Gap statement. The pharmacokinetic/pharmacodynamic (PK/PD) characteristics of both types of colistin… read more here.
Keywords: producing klebsiella; adaptive resistance; resistance; carbapenemase producing ... See more keywords