Identification of the Major Product of Guanine Oxidation in DNA by Ozone.
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DOI: 10.1021/acs.chemrestox.2c00103
Abstract: Ozonolysis of guanosine formed the 5-carboxamido-5-formamido-2-iminohydantoin (2Ih) nucleoside along with trace spiroiminodihydantoin (Sp). On the basis of literature precedent, we propose an unconventional ozone mechanism involving incorporation of only one oxygen atom of O3 to… read more here.
Keywords: identification major; product guanine; ozone; oxidation dna ... See more keywords