Assessing the impact of product inhibition in a chromogenic assay.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2019.05.001
Abstract: Chromogenic substrates (CS) are synthetic substrates used to monitor the activity of a target enzyme. It has been reported that some CSs display competitive product inhibition with their target enzyme. Thus, in assays where enzyme… read more here.
Keywords: biochemistry; impact product; chromogenic assay; product ... See more keywords
Steady-state current in product inhibition kinetics in an amperometric biosensor: Adomian decomposition and Taylor series method
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Electroanalytical Chemistry"
DOI: 10.1016/j.jelechem.2021.115103
Abstract: Abstract Theoretical models of an amperometric biosensor with product inhibition kinetics are discussed. These models are based on non-stationary diffusion equations containing a non-linear term related to non-Michaelis-Menten kinetics of the enzymatic reaction. The approximate… read more here.
Keywords: inhibition kinetics; method; product inhibition; product ... See more keywords