NICEpath: Finding metabolic pathways in large networks through atom-conserving substrate–product pairs
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab368
Abstract: Abstract Motivation Finding biosynthetic pathways is essential for metabolic engineering of organisms to produce chemicals, biodegradation prediction of pollutants and drugs, and for the elucidation of bioproduction pathways of secondary metabolites. A key step in… read more here.
Keywords: biochemical networks; metabolic pathways; product; metabolic networks ... See more keywords
PyMiner: A method for metabolic pathway design based on the uniform similarity of substrate-product pairs and conditional search
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0266783
Abstract: Metabolic pathway design is an essential step in the course of constructing an efficient microbial cell factory to produce high value-added chemicals. Meanwhile, the computational design of biologically meaningful metabolic pathways has been attracting much… read more here.
Keywords: metabolic pathway; pathway design; substrate product; design ... See more keywords