A New Family of Jumonji C Domain-Containing KDM Inhibitors Inspired by Natural Product Purpurogallin
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DOI: 10.3389/fchem.2020.00312
Abstract: Aberrant epigenetic modifications are involved in cancer development. Jumonji C domain-containing histone lysine demethylases (KDMs) are found mainly up-regulated in breast, prostate, and colon cancer. Currently, growing interest is focusing on the identification and development… read more here.
Keywords: domain containing; purpurogallin; natural product; product purpurogallin ... See more keywords