Process performance and product quality in an integrated continuous antibody production process
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26069
Abstract: Continuous manufacturing is currently being seriously considered in the biopharmaceutical industry as the possible new paradigm for producing therapeutic proteins, due to production cost and product quality related benefits. In this study, a monoclonal antibody… read more here.
Keywords: process; product quality; production; integrated continuous ... See more keywords
Multi‐omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer, and product quality
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27899
Abstract: A robust monoclonal antibody (mAb) bioprocess requires physiological parameters such as temperature, pH, or dissolved oxygen to be well‐controlled as even small variations in them could potentially impact the final product quality. For instance, pH… read more here.
Keywords: culture; cell; product quality; multi omics ... See more keywords
Probing the importance of clonality: Single cell subcloning of clonally derived CHO cell lines yields widely diverse clones differing in growth, productivity, and product quality
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Progress"
DOI: 10.1002/btpr.2594
Abstract: In the past few decades, a large variety of therapeutic antibodies and proteins have been expressed in Chinese hamster ovary (CHO) cells. This mammalian expression system is robust, scalable, relatively inexpensive, and importantly allows for… read more here.
Keywords: single cell; cell lines; product quality; cell ... See more keywords
Improving Product Quality and Productivity of Bispecific Molecules Through the Application of Continuous Perfusion Principles.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology progress"
DOI: 10.1002/btpr.2973
Abstract: Bispecific protein scaffolds can be more complex than traditional monoclonal antibodies (MAbs) because two different sites/domains for epitope binding are needed. Because of this increased molecular complexity, bispecific molecules are difficult to express and can… read more here.
Keywords: perfusion; product; process; product quality ... See more keywords
Honesty, Deception, or Collusion? Quality Information Disclosure in Live Streaming Commerce
Sign Up to like & getrecommendations! Published in 2025 at "Managerial and Decision Economics"
DOI: 10.1002/mde.70038
Abstract: This study employs a Stackelberg game‐theoretic framework to analyze three scenarios of product quality disclosure: honest disclosure of product quality to both consumers and influencers; deceptive disclosure of the actual quality to both influencers and… read more here.
Keywords: quality; information; collusion; disclosure ... See more keywords
Signaling endogenous product quality with price in the presence of consumer boycotts
Sign Up to like & getrecommendations! Published in 2025 at "Southern Economic Journal"
DOI: 10.1002/soej.12757
Abstract: This paper constructs a two‐period model of price signaling, where an entry firm sells experience goods with endogenous product quality while its cost efficiency of producing quality and product quality may be private information at… read more here.
Keywords: quality; quality price; endogenous product; product quality ... See more keywords
The regulatory warning model of regional product quality based on the back-propagation artificial neural network
Sign Up to like & getrecommendations! Published in 2019 at "Neural Computing and Applications"
DOI: 10.1007/s00521-019-04188-8
Abstract: Accidents of product quality occur in food, medicine and industrial products, posing a major risk to consumers. Prediction and control of accidents spread are difficult, mainly due to the complexity of the interaction between stakeholders… read more here.
Keywords: product; regional product; product quality; warning model ... See more keywords
When does online review matter to consumers? The effect of product quality information cues
Sign Up to like & getrecommendations! Published in 2020 at "Electronic Commerce Research"
DOI: 10.1007/s10660-020-09398-0
Abstract: Word of Mouth (WOM) is powerful, and online reviews are often the most accessible WOM information source in electronic commerce. Maintaining favorable online reputation has been the top priority for businesses, and investments in improving… read more here.
Keywords: information cues; information; online reviews; product ... See more keywords
An information integration and transmission model of multi-source data for product quality and safety
Sign Up to like & getrecommendations! Published in 2019 at "Information Systems Frontiers"
DOI: 10.1007/s10796-016-9727-x
Abstract: The product quality and safety information have drawn extensive attention due to social impacts. Based on the transmission characteristics of the Web information, we constructed the information transmission models with government intervention and without government… read more here.
Keywords: quality safety; intervention; government; transmission ... See more keywords
The effect of context attractiveness on product attractiveness and product quality: the moderating role of product familiarity
Sign Up to like & getrecommendations! Published in 2017 at "Marketing Letters"
DOI: 10.1007/s11002-016-9404-3
Abstract: Prior research has investigated a number of drivers of consumers’ perceived product attractiveness, such as a product’s shape and color. The context, in which a product is presented, has so far been largely neglected in… read more here.
Keywords: product attractiveness; context; product; attractiveness product ... See more keywords
Social interactions and product quality: the value of pooling in cooperative entrepreneurial networks
Sign Up to like & getrecommendations! Published in 2018 at "Small Business Economics"
DOI: 10.1007/s11187-017-9893-3
Abstract: Why do cooperatives often pay a pooled price, despite the free-riding incentives it entails? In this paper, we highlight that a cooperative is an enterprise owned by a network of entrepreneurial members. By taking explicitly… read more here.
Keywords: interactions product; product quality; quality value; social interactions ... See more keywords