Systematizing the different notions of growth-coupled product synthesis and a single framework for computing corresponding strain designs.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology journal"
DOI: 10.1002/biot.202100236
Abstract: BACKGROUND A widely used design principle for metabolic engineering of microorganisms aims to introduce interventions that enforce growth-coupled product synthesis such that the product of interest becomes a (mandatory) by-product of growth. However, different variants… read more here.
Keywords: growth coupled; product; product synthesis; strain designs ... See more keywords
1,2-Anti aldol methodologies used in natural product synthesis
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DOI: 10.1016/j.tet.2019.130618
Abstract: Abstract This review covers the methods of making 1,2-anti aldols that have been used in the synthesis of natural products or chiral sections of such compounds. The literature coverage is from 2013 until September 2018. read more here.
Keywords: methodologies used; anti aldol; used natural; product synthesis ... See more keywords
A Modular, Argon-Driven Flow Platform for Natural Product Synthesis and Late-Stage Transformations.
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DOI: 10.1021/acs.orglett.1c00661
Abstract: A modular flow platform for natural product synthesis was designed. To access different reaction setups with a maximum of flexibility, interchangeable 3D-printed components serve as backbone. By switching from liquid- to gas-driven flow, reagent and… read more here.
Keywords: product synthesis; platform natural; flow platform; natural product ... See more keywords
Metal-mediated C–O bond forming reactions in natural product synthesis
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DOI: 10.1039/c7qo00671c
Abstract: Metal catalyzed reactions for the formation of C–O bonds have had a dramatic impact in natural product synthesis over the past few decades. Various metals have been reported to efficiently catalyze cross-coupling reactions for the… read more here.
Keywords: product synthesis; bond; reactions natural; natural product ... See more keywords