A Novel Approach for the Production of Aggregation-Prone Proteins Using the Spidroin-Derived NT* Tag.
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DOI: 10.1007/978-1-0716-1859-2_6
Abstract: Spiders have evolved proteins that can be kept in a highly concentrated soluble form in the silk gland yet rapidly assemble into stable silk fibers under certain environmental conditions. The transition between soluble and fibrillar… read more here.
Keywords: aggregation; tag; aggregation prone; production aggregation ... See more keywords
Kinetic models reveal the interplay of protein production and aggregation
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DOI: 10.1039/d4sc00088a
Abstract: Protein aggregation is a key process in the development of many neurodegenerative disorders, including dementias such as Alzheimer's disease. Significant progress has been made in understanding the molecular mechanisms of aggregate formation in pure buffer… read more here.
Keywords: aggregation prone; protein; aggregation; production aggregation ... See more keywords