Adaptive Evolution in Producing Microtiter Cultivations Generates Genetically Stable Escherichia coli Production Hosts for Continuous Bioprocessing
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Journal"
DOI: 10.1002/biot.202000376
Abstract: The production of recombinant proteins usually reduces cell fitness and the growth rate of producing cells. The growth disadvantage favors faster‐growing non‐producer mutants. Therefore, continuous bioprocessing is hardly feasible in Escherichia coli due to the… read more here.
Keywords: continuous bioprocessing; production; escherichia coli; long term ... See more keywords
Peculiar properties of BK-8 hard alloy wear after volumetric laser pulsed hardening under production conditions
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Friction and Wear"
DOI: 10.3103/s1068366617020167
Abstract: Today, it is considered that the latest principally new breakthrough in the sphere of tooling materials was the invention of metal-ceramic solid alloys in the 1930s. Moreover, model materials for cutting tools have slowed down… read more here.
Keywords: alloy; laser; peculiar properties; wear ... See more keywords
Roughness of Production Conditions: Does It Really Affect Stability of IgG-Based Antivenoms?
Sign Up to like & getrecommendations! Published in 2022 at "Toxins"
DOI: 10.3390/toxins14070483
Abstract: Antivenoms contain either pure animal IgGs or their fragments as an active substance, and are the only specific therapeutics against envenomation arising from snakebites. Although they are highly needed, the low sustainability of such preparations’… read more here.
Keywords: conditions really; roughness production; production conditions; stability ... See more keywords