Microbial Engineering for Production of NâFunctionalized Amino Acids and Amines
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DOI: 10.1002/biot.201900451
Abstract: Nâfunctionalized amines play important roles in nature and occur, for example, in the antibiotic vancomycin, the immunosuppressant cyclosporine, the cytostatic actinomycin, the siderophore aerobactin, the cyanogenic glucoside linamarin, and the polyamine spermidine. In the pharmaceutical… read more here.
Keywords: functionalized amines; engineering; functionalized amino; microbial engineering ... See more keywords
Preparative Production of Functionalized (N- and O-Heterocyclic) Polycyclic Aromatic Hydrocarbons by Human Cytochrome P450 3A4 in a Bioreactor
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DOI: 10.3390/biom12020153
Abstract: Polycyclic aromatic hydrocarbons (PAHs) and their N- and O-containing derivatives (N-/O-PAHs) are environmental pollutants and synthetically attractive building blocks in pharmaceuticals. Functionalization of PAHs can be achieved via C-H activation by cytochrome P450 enzymes (e.g.,… read more here.
Keywords: aromatic hydrocarbons; polycyclic aromatic; cytochrome p450; production functionalized ... See more keywords