Yes‐Associated Protein in Kupffer Cells Enhances the Production of Proinflammatory Cytokines and Promotes the Development of Nonalcoholic Steatohepatitis
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30990
Abstract: Yes‐associated protein (YAP) plays an important role in hepatocarcinogenesis, although the potential role of YAP in non‐neoplastic liver diseases remains largely unknown. We report herein that YAP in Kupffer cells (KCs) enhances the production of… read more here.
Keywords: associated protein; proinflammatory cytokines; kupffer cells; production proinflammatory ... See more keywords
RhoB induces the production of proinflammatory cytokines in TLR‐triggered macrophages
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Immunology"
DOI: 10.1016/j.molimm.2017.04.015
Abstract: HighlightsTLR agonists (LPS, CpG, poly(I:C)) induce RhoB expression in macrophages.RhoB increases the production of proinflammatory mediators in macrophages upon TLR agonists stimulation.RhoB induces LPS‐initiated signaling pathways, including phosphorylation of Btk, I&kgr;B&agr;, JNK, Erk and p38… read more here.
Keywords: rhob; rhob induces; macrophages rhob; tlr triggered ... See more keywords
Lactobacillus gasseri Suppresses the Production of Proinflammatory Cytokines in Helicobacter pylori-Infected Macrophages by Inhibiting the Expression of ADAM17
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.02326
Abstract: The ability of Helicobacter pylori to evade the host immune system allows the bacterium to colonize the host for a lifetime. Long-term infection with H. pylori causes chronic inflammation, which is the major risk factor… read more here.
Keywords: proinflammatory cytokines; helicobacter pylori; host; production proinflammatory ... See more keywords