The β-catenin signaling pathway stimulates bovine herpesvirus 1 productive infection.
Sign Up to like & getrecommendations! Published in 2017 at "Virology"
DOI: 10.1016/j.virol.2016.10.014
Abstract: Bovine herpes virus 1 (BoHV-1), an important bovine pathogen, causes conjunctivitis and disorders in the upper respiratory tract. Following acute infection, BoHV1 establishes life-long latency in sensory neurons. Recent studies demonstrated that viral gene products… read more here.
Keywords: catenin signaling; infection; signaling pathway; productive infection ... See more keywords
Effects of the synthetic corticosteroid dexamethasone on bovine herpesvirus 1 productive infection.
Sign Up to like & getrecommendations! Published in 2017 at "Virology"
DOI: 10.1016/j.virol.2017.02.012
Abstract: Sensory neurons are a primary site for life-long latency of bovine herpesvirus 1 (BoHV-1). The synthetic corticosteroid dexamethasone induces reactivation from latency and productive infection, in part because the BoHV-1 genome contains more than 100… read more here.
Keywords: corticosteroid dexamethasone; bovine herpesvirus; synthetic corticosteroid; infection ... See more keywords
Progesterone Sporadically Induces Reactivation from Latency in Female Calves but Proficiently Stimulates Bovine Herpesvirus 1 Productive Infection
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.02130-21
Abstract: Steroid hormone fluctuations are predicted to enhance or initiate bovine herpesvirus 1 (BoHV-1) replication and virus spread in cattle. For example, stress increases the incidence of BoHV-1 reactivation from latency in cattle, and the synthetic… read more here.
Keywords: productive infection; reactivation; reactivation latency; progesterone ... See more keywords
NFAT5 Restricts Bovine Herpesvirus 1 Productive Infection in MDBK Cell Cultures
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00117-23
Abstract: Accumulating studies have revealed that NFAT5 regulates disease development due to infection of numerous viruses, underlying the importance of the host factor in virus pathogenesis. Here, we report that NFAT5 has capacity to restrict BoHV-1… read more here.
Keywords: productive infection; virus infection; infection; nfat5 ... See more keywords
Bovine Herpesvirus 1 Productive Infection Led to Inactivation of Nrf2 Signaling through Diverse Approaches
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DOI: 10.1155/2019/4957878
Abstract: Bovine herpesvirus type 1 (BoHV-1) is a significant cofactor for bovine respiratory disease complex (BRDC), the most important inflammatory disease in cattle. BoHV-1 infection in cell cultures induces overproduction of pathogenic reactive oxygen species (ROS)… read more here.
Keywords: bovine herpesvirus; infection; nrf2 signaling; bohv infection ... See more keywords
SARS-CoV-2 Establishes a Productive Infection in Hepatoma and Glioblastoma Multiforme Cell Lines
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DOI: 10.3390/cancers15030632
Abstract: Simple Summary A novel coronavirus that causes a worldwide pandemic poses a significant threat to patients. The virus can induce not only a cytokine storm and thrombosis but also various extra-respiratory diseases such as liver… read more here.
Keywords: productive infection; glioblastoma; infection; cell lines ... See more keywords
Non-Productive Infection of Glial Cells with SARS-CoV-2 in Hamster Organotypic Cerebellar Slice Cultures
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14061218
Abstract: The numerous neurological syndromes associated with COVID-19 implicate an effect of viral pathogenesis on neuronal function, yet reports of direct SARS-CoV-2 infection in the brain are conflicting. We used a well-established organotypic brain slice culture… read more here.
Keywords: productive infection; hamster; infection; sars cov ... See more keywords