Articles with "products dabrafenib" as a keyword



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LC-MS/MS studies for identification and characterization of new forced degradation products of dabrafenib and establishment of their degradation pathway.

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Published in 2021 at "Journal of pharmaceutical and biomedical analysis"

DOI: 10.1016/j.jpba.2021.114351

Abstract: Dabrafenib (Tafinlar) is used for the treatment of patients with BRAF V600 mutation positive unresectable or metastatic melanoma. Forced degradation study of the drug product and drug substance is very much important in drug development… read more here.

Keywords: degradation; study; products dabrafenib; drug ... See more keywords