Natural Products in the "Marketplace": Interfacing Synthesis and Biology.
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DOI: 10.1021/jacs.8b11297
Abstract: Drugs are discovered through the biological screening of collections of compounds, followed by optimization toward functional end points. The properties of screening collections are often balanced between diversity, physicochemical favorability, intrinsic complexity, and synthetic tractability… read more here.
Keywords: natural products; biology; doi 1016; doi ... See more keywords